VAMP2 antibody (AA 1-89)

Catalog No. ABIN7596091

The Mouse Monoclonal anti-VAMP2 antibody has been validated for WB, ELISA, ICC and IF. It is suitable to detect VAMP2 in samples from Human.

Quick Overview for VAMP2 antibody (AA 1-89) (ABIN7596091)

Target: VAMP2 (Vesicle-Associated Membrane Protein 2 (Synaptobrevin 2) (VAMP2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This VAMP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Clone: 3E5

Product Details anti-VAMP2 Antibody

Binding Specificity: AA 1-89

Purpose: Human VAMP-2 antibody

Purification: protein-A affinity chromatography

Immunogen: Recombinant human Synaptobrevin 2 (1-89aa) purified from E. coli

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycero

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Target Details for VAMP2

Target: VAMP2 (Vesicle-Associated Membrane Protein 2 (Synaptobrevin 2) (VAMP2))

Alternative Name: VAMP-2

Background: Synaptobrevin 2 (Vesicle-associated membrane, VAMP2), which is an 18 kDa integral membrane proteinlocalized to the cytoplasmic surface of synaptic vesicle, consists of a proline-rich N-terminal region, a highlyconserved hydrophilic domain, followed by a transmembrane anchor and a C-terminal tail. Synaptobrevin 2 ispredominantly expressed in Langerhans islets and glomerular cells. The N-terminal domain of the protein forms aspecific SNARE complex with the target membrane-associated t- or Q-SNAREs syntaxin 1 and SNAP-25.This antibody recognizes specifically synaptobrevin 2, but it also shows a low affinity to synaptobrevin1.

NCBI Accession: NP_055047

Pathways: Peptide Hormone Metabolism, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport