Syntaxin 6 antibody (AA 1-239)

Catalog No. ABIN7599139

This Rabbit Polyclonal antibody specifically detects Syntaxin 6 in ELISA, WB, IF, ICC and FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Syntaxin 6 antibody (AA 1-239) (ABIN7599139)

Target: Syntaxin 6 (STX6)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Syntaxin 6 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Product Details anti-Syntaxin 6 Antibody

Binding Specificity: AA 1-239

Purpose: Anti-Syntaxin 6/STX6 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-Syntaxin 6/STX6 Antibody Picoband® (ABIN7599139). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Syntaxin 6/STX6 recombinant protein (Position: M1-A239).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Advani, R. J., Bae, H.-R., Bock, J. B., Chao, D. S., Doung, Y.-C., Prekeris, R., Yoo, J.-S., Scheller, R. H. Seven novel mammalian SNARE proteins localize to distinct membrane compartments. J. Biol. Chem. 273: 10317-10324, 1998. 2. Charest, A., Lane, K., McMahon, K., Housman, D. E. Association of a novel PDZ domain-containing peripheral Golgi protein with the Q-SNARE (Q-soluble N-ethylmaleimide-sensitive fusion protein (NSF) attachment protein receptor) protein syntaxin 6. J. Biol. Chem. 276: 29456-29465, 2001. 3. Cheng, J., Cebotaru, V., Cebotaru, L., Guggino, W. B. Syntaxin 6 and CAL mediate the degradation of the cystic fibrosis transmembrane conductance regulator. Molec. Biol. Cell 21: 1178-1187, 2010.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for Syntaxin 6

Target: Syntaxin 6 (STX6)

Alternative Name: STX6

Background:

Synonyms: Semaphorin-3B, Sema A (V), Semaphorin-V, Sema V, SEMA3B, SEMA5, SEMAA

Tissue Specificity: Expressed abundantly but differentially in a variety of neural and nonneural tissues.

Background: Syntaxin-6 is a protein that in humans is encoded by the STX6 gene. Enables syntaxin binding activity. Involved in several processes, including Golgi ribbon formation, retrograde transport, endosome to Golgi, and vesicle fusion. Acts upstream of or within endocytic recycling. Located in several cellular components, including early endosome, perinuclear region of cytoplasm, and trans-Golgi network. Part of SNARE complex.

Molecular Weight: 29 kDa

Gene ID: 10228

UniProt: O43752

Pathways: Synaptic Vesicle Exocytosis