ALDH1A2 antibody (AA 1-318)

Catalog No. ABIN7599264

This anti-ALDH1A2 antibody is a Rabbit Polyclonal antibody detecting ALDH1A2 in WB and ELISA. Suitable for Human.

Quick Overview for ALDH1A2 antibody (AA 1-318) (ABIN7599264)

Target: ALDH1A2 (Aldehyde Dehydrogenase 1 Family, Member A2 (ALDH1A2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALDH1A2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ALDH1A2 Antibody

Binding Specificity: AA 1-318

Purpose: Anti-ALDH1A2 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-ALDH1A2 Antibody Picoband® (ABIN7599264). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human ALDH1A2 recombinant protein (Position: M1-Q318).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. "Entrez Gene: ALDH1A2 aldehyde dehydrogenase 1 family, member A2". 2. Ono Y, Fukuhara N, Yoshie O (Dec 1998). "TAL1 and LIM-Only Proteins Synergistically Induce Retinaldehyde Dehydrogenase 2 Expression in T-Cell Acute Lymphoblastic Leukemia by Acting as Cofactors for GATA3". Mol Cell Biol 18 (12): 6939-50.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for ALDH1A2

Target: ALDH1A2 (Aldehyde Dehydrogenase 1 Family, Member A2 (ALDH1A2))

Alternative Name: ALDH1A2

Background:

Synonyms: ADP-ribosylation factor GTPase-activating protein 1,ARF GAP 1,ADP-ribosylation factor 1 GTPase-activating protein,ARF1 GAP,ARF1-ed GTPase-activating protein,ARFGAP1,ARF1GAP,

Tissue Specificity: Ubiquitous. .

Background: Aldehyde dehydrogenase 1 family, member A2, also known as ALDH1A2 or retinaldehyde dehydrogenase 2 (RALDH2), is an enzyme that in humans is encoded by the ALDH1A2 gene. This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Four transcript variants encoding distinct isoforms have been identified for this gene.

Molecular Weight: 57 kDa

Gene ID: 8854

UniProt: O94788

Pathways: Retinoic Acid Receptor Signaling Pathway