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ELL antibody (AA 1-407)

This anti-ELL antibody is a Rabbit Polyclonal antibody detecting ELL in WB, ELISA, IF, ICC and FACS. Suitable for Human.
Catalog No. ABIN7599363

Quick Overview for ELL antibody (AA 1-407) (ABIN7599363)

Target

See all ELL Antibodies
ELL (Elongation Factor RNA Polymerase II (ELL))

Reactivity

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Human

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This ELL antibody is un-conjugated

Application

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)
  • Binding Specificity

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    AA 1-407

    Purpose

    Anti-ELL Antibody Picoband®

    Cross-Reactivity (Details)

    No cross-reactivity with other proteins.

    Characteristics

    Anti-ELL Antibody Picoband® (ABIN7599363). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Purification

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human ELL recombinant protein (Position: M1-S407).

    Isotype

    IgG
  • Application Notes

    Western blot, 0.25-0.5 μg/mL, Human
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Lavau, C., Luo, R. T., Du, C., Thirman, M. J. Retrovirus-mediated gene transfer of MLL-ELL transforms primary myeloid progenitors and causes acute myeloid leukemias in mice. Proc. Nat. Acad. Sci. 97: 10984-10989, 2000. 2. Shilatifard, A., Lane, W. S., Jackson, K. W., Conaway, R. C., Conaway, J. W. An RNA polymerase II elongation factor encoded by the human ELL gene. Science 271: 1873-1876, 1996. 3. Thirman, M. J., Levitan, D. A., Kobayashi, H., Simon, M. C., Rowley, J. D. Cloning of ELL, a gene that fuses to MLL in a t(11,19)(q23,p13.1) in acute myeloid leukemia. Proc. Nat. Acad. Sci. 91: 12110-12114, 1994.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Concentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Storage

    4 °C,-20 °C

    Storage Comment

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target

    ELL (Elongation Factor RNA Polymerase II (ELL))

    Alternative Name

    ELL

    Background

    Synonyms: Glutathione S-transferase Mu 3, GST class-mu 3, GSTM3-3, hGSTM3-3, GSTM3, GST5,

    Tissue Specificity: Testis and brain.

    Background: RNA polymerase II elongation factor ELL is an enzyme that in humans is encoded by the ELL gene. Eleven-nineteen lysine-rich leukemia protein (ELL) was originally identified in a screen for genes that fuse to MLL (myeloid-lymphoid leukemia) in the t(11,19)(q23,p13.1) breakpoint. ELL is an elongation factor that increases the catalytic rate of RNA pol II by suppressing transient pausing of RNA pol II. ELL has been shown to be essential to development and important to cell growth and survival. Alternate names for ELL include RNA polymerase II elongation factor ELL, ELL1, and men.

    Molecular Weight

    60-80 kDa

    Gene ID

    8178

    UniProt

    P55199
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