DOCK1 antibody (AA 100-1732)

Catalog No. ABIN7599615

This anti-DOCK1 antibody is a Rabbit Polyclonal antibody detecting DOCK1 in WB, ELISA, IHC, IF and FACS. Suitable for Human.

Quick Overview for DOCK1 antibody (AA 100-1732) (ABIN7599615)

Target: DOCK1 (Dedicator of Cytokinesis 1 (DOCK1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOCK1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-DOCK1 Antibody

Binding Specificity: AA 100-1732

Purpose: Anti-DOCK180/DOCK1 Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-DO/DOCK1 Antibody (ABIN7599615). Tested in ELISA, Flow Cytometry, IF, IHC, WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human DOCK180/DOCK1 recombinant protein (Position: S100-T1732).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunofluorescence, 5 μg/mL, Humann
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for DOCK1

Target: DOCK1 (Dedicator of Cytokinesis 1 (DOCK1))

Alternative Name: DOCK1

Background:

Synonyms: Tumor necrosis factor-inducible gene 6 protein,Hyaluronate-binding protein,TNF-stimulated gene 6 protein,TSG-6,Tumor necrosis factor alpha-induced protein 6,TNF alpha-induced protein 6,TNFAIP6,TSG6,

Tissue Specificity: Found in the synovial fluid of patients with rheumatoid arthritis. .

Background: Dock180, (Dedicator of cytokinesis) also known as DOCK1, is a large (~180 kDa) protein involved in intracellular signalling networks. This gene encodes a member of the dedicator of cytokinesis protein family. Dedicator of cytokinesis proteins act as guanine nucleotide exchange factors for small Rho family G proteins. The encoded protein regulates the small GTPase Rac, thereby influencing several biological processes, including phagocytosis and cell migration. Overexpression of this gene has also been associated with certain cancers. Alternative splicing results in multiple transcript variants.

Molecular Weight: 215 kDa

Gene ID: 1793

UniProt: Q14185

Pathways: Signaling of Hepatocyte Growth Factor Receptor