INSM2 antibody (AA 11-529)

Catalog No. ABIN7599727

Product Details anti-INSM2 Antibody

Target: INSM2 (Insulinoma-Associated 2 (INSM2))

Binding Specificity: AA 11-529

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This INSM2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Anti-INSM2 Antibody Picoband®

Characteristics: Anti-INSM2 Antibody Picoband® (ABIN7599727). Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human INSM2 recombinant protein (Position: K11-H529). Human INSM2 shares 62.4% amino acid (aa) sequence identity with mouse INSM2.

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Cai, T., Chen, X., Wang, R., Xu, H., You, Y., Zhang, T., Lan, M. S., Notkins, A. L. Expression of insulinoma-associated 2 (INSM2) in pancreatic islet cells is regulated by the transcription factors Ngn3 and NeuroD1. Endocrinology 152: 1961-1969, 2011. 2. Wang, L., Sun, Z. S., Xiang, B., Wei, C., Wang, Y., Sun, K., Chen, G., Lan, M. S., Carmona, G. N., Notkins, A. L., Cai, T. Targeted deletion of Insm2 in mice result (sic) in reduced insulin secretion and glucose intolerance. J. Transl. Med. 16: 297, 2018. Note: Electronic Article.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for INSM2

Target: INSM2 (Insulinoma-Associated 2 (INSM2))

Alternative Name: INSM2 (INSM2 Products)

Background: INSM2 may function as a growth suppressor or tumor suppressor in liver cells and in certain neurons.

Molecular Weight: 69 kDa

Gene ID: 84684

UniProt: Q96T92