NLRP9 antibody (AA 118-746)

Catalog No. ABIN7599799

This anti-NLRP9 antibody is a Rabbit Polyclonal antibody detecting NLRP9 in ELISA and WB. Suitable for Human.

Quick Overview for NLRP9 antibody (AA 118-746) (ABIN7599799)

Target: NLRP9 (NLR Family, Pyrin Domain Containing 9 (NLRP9))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NLRP9 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-NLRP9 Antibody

Binding Specificity: AA 118-746

Purpose: Anti-NLRP9 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-NLRP9 Antibody Picoband® (ABIN7599799). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human NLRP9 recombinant protein (Position: H118-H746).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Inohara, N., Nunez, G. NODs: intracellular proteins involved in inflammation and apoptosis. Nature Rev. Immun. 3: 371-382, 2003. 2. Tschopp, J., Martinon, F., Burns, K. NALPs: a novel protein family involved in inflammation. Nature Rev. Molec. Cell Biol. 4: 95-104, 2003. 3. Zhu, S., Ding, S., Wang, P., Wei, Z., Pan, W., Palm, N. W., Yang, Y., Yu, H., Li, H.-B., Wang, G., Lei, X., de Zoete, M. R., and 13 others. Nlrp9b inflammasome restricts rotavirus infection in intestinal epithelial cells. Nature 546: 667-670, 2017.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for NLRP9

Target: NLRP9 (NLR Family, Pyrin Domain Containing 9 (NLRP9))

Alternative Name: NLRP9

Background:

Synonyms: RNA-binding protein 47,RNA-binding motif protein 47,RBM47,

Tissue Specificity: Abundantly expressed in tonsil, lymph node, and trachea, strong expression in prostate, lower expression in thyroid, stomach, and colon. .

Background: The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). This protein may play a regulatory role in the innate immune system as similar family members belong to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5.

Molecular Weight: 113 kDa

Gene ID: 338321

Pathways: Inflammasome