TYR antibody (AA 130-529)

Catalog No. ABIN7599956

This Rabbit Polyclonal antibody specifically detects TYR in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for TYR antibody (AA 130-529) (ABIN7599956)

Target: TYR (Tyrosinase (TYR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TYR antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-TYR Antibody

Binding Specificity: AA 130-529

Purpose: Anti-Tyrosinase/TYR Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-Tyrosinase/TYR Antibody (ABIN7599956). Tested in ELISA, WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Tyrosinase/TYR recombinant protein (Position: E130-K529).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for TYR

Target: TYR (Tyrosinase (TYR))

Alternative Name: TYR

Background:

Synonyms: Bone morphogenetic protein receptor type-2, BMP type-2 receptor, BMPR-2, Bone morphogenetic protein receptor type II, BMP type II receptor, BMPR-II, BMPR2, PPH1

Tissue Specificity: Highly expressed in heart and liver.

Background: The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene.

Molecular Weight: 60-65 kDa

Gene ID: 7299

UniProt: P14679