AGLU antibody (AA 131-2697)
Quick Overview for AGLU antibody (AA 131-2697) (ABIN7599961)
Target
See all AGLU AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 131-2697
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Purpose
- Anti-MGAM Antibody
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Cross-Reactivity (Details)
- No cross-reactivity with other proteins.
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Characteristics
- Anti-MGAM Antibody (ABIN7599961). Tested in ELISA, IHC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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Purification
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human MGAM recombinant protein (Position: Y131-I2697).
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Isotype
- IgG
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Application Notes
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Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg /1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Storage
- 4 °C,-20 °C
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Storage Comment
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- AGLU (alpha-Glucosidase (AGLU))
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Alternative Name
- MGAM
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Background
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Synonyms: Mesoderm posterior protein 1, Class C basic helix-loop-helix protein 5, bHLHc5, MESP1, BHLHC5
Tissue Specificity: Highly expressed in brain and weakly in heart, small intestine and uterus. Isoform 1A is mostly expressed in granular cell and molecular layer. Isoform 1B is mostly expressed in Purkinje cells. Isoform 1E is predominantly expressed in peripheral tissues as kidney, lung, trachea, colon, small intestine, stomach, bone marrow, thymus and mammary gland. .
Background: Maltase-glucoamylase, intestinal is an enzyme that in humans is encoded by the MGAM gene. This gene encodes maltase-glucoamylase, which is a brush border membrane enzyme that plays a role in the final steps of digestion of starch. The protein has two catalytic sites identical to those of sucrase-isomaltase, but the proteins are only 59 % homologous. Both are members of glycosyl hydrolase family 31, which has a variety of substrate specificities.
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Molecular Weight
- 240 kDa
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Gene ID
- 8972
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UniProt
- O43451
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Pathways
- Cellular Glucan Metabolic Process
Target
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