Cadherin 13 antibody (AA 149-692)

Catalog No. ABIN7600095

The Rabbit Polyclonal anti-Cadherin 13 antibody is suitable to detect Cadherin 13 in samples from Human and Rat. It has been validated for WB, IHC, ELISA, ICC, FACS and IF.

Quick Overview for Cadherin 13 antibody (AA 149-692) (ABIN7600095)

Target: Cadherin 13 (CDH13)

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cadherin 13 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunofluorescence (IF)

Product Details anti-Cadherin 13 Antibody

Binding Specificity: AA 149-692

Purpose: Anti-H Cadherin/CDH13 Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-H Cadherin/CDH13 Antibody. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human H Cadherin/CDH13 recombinant protein (Position: E149-A692).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human Immunohistochemistry (Paraffin-embedded Section), 1-2 μg/mL, Human, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Cadherin 13

Target: Cadherin 13 (CDH13)

Alternative Name: CDH13

Background:

Background: T-cadherin also known as cadherin 13, H-cadherin (heart) (CDH13) is a unique member of cadherin superfamily because it lacks the transmembrane and cytoplasmic domains and is anchored to the cells membrane through the GPI anchor. This protein acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis. The gene is hypermethylated in many types of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene Full Name: cadherin 13

Molecular Weight: 105 kDa, 130 kDa

Gene ID: 1012

UniProt: P55290

Pathways: EGFR Signaling Pathway, Cell-Cell Junction Organization