NTSR1 antibody (AA 15-400)

Catalog No. ABIN7600109

This Rabbit Polyclonal antibody specifically detects NTSR1 in WB, ELISA and FACS. It exhibits reactivity toward Human.

Quick Overview for NTSR1 antibody (AA 15-400) (ABIN7600109)

Target: NTSR1 (Neurotensin Receptor 1 (High Affinity) (NTSR1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NTSR1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-NTSR1 Antibody

Binding Specificity: AA 15-400

Purpose: Anti-Neurotensin Receptor 1/NTSR1 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-Neurotensin Receptor 1/NTSR1 Antibody Picoband® (ABIN7600109). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Neurotensin Receptor 1/NTSR1 recombinant protein (Position: A15-D400).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Huang, W., Masureel, M., Qu, Q., Janetzko, J., Inoue, A., Kato, H. E., Robertson, M. J., Nguyen, K. C., Glenn, J. S., Skiniotis, G., Kobilka, B. K. Structure of the neurotensin receptor 1 in complex with beta-arrestin 1. Nature 579: 303-308, 2020. 2. Kato, H. E., Zhang, Y., Hu, H., Suomivuori, C.-M., Kadji, F. M. N., Aoki, J., Krishna Kumar, K., Fonseca, R., Hilger, D., Huang, W., Latorraca, N. R., Inoue, A., Dror, R. O., Kobilka, B. K., Skiniotis, G. Conformational transitions of a neurotensin receptor 1-G(i1) complex. Nature 572: 80-85, 2019. 3. Laurent, P., Clerc, P., Mattei, M.-G., Forgez, P., Dumont, X., Ferrara, P., Caput, D., Rostene, W. Chromosomal localization of mouse and human neurotensin receptor genes. Mammalian Genome 5: 303-306, 1994.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for NTSR1

Target: NTSR1 (Neurotensin Receptor 1 (High Affinity) (NTSR1))

Alternative Name: NTSR1

Background:

Synonyms: Thioredoxin, mitochondrial, MTRX, Mt-Trx, Thioredoxin-2, TXN2, TRX2

Tissue Specificity: Widely expressed in adult (at protein level) and fetal tissues.

Background: Neurotensin receptor type 1 is a protein that in humans is encoded by the NTSR1 gene. Neurotensin receptor 1 belongs to the large superfamily of G-protein coupled receptors. NTSR1 mediates the multiple functions of neurotensin, such as hypotension, hyperglycemia, hypothermia, antinociception, and regulation of intestinal motility and secretion.

Molecular Weight: 43 kDa

Gene ID: 4923

UniProt: P30989