HELLS antibody (AA 167-838)

Catalog No. ABIN7600237

The Rabbit Polyclonal anti-HELLS antibody is suitable to detect HELLS in samples from Human and Mouse. It has been validated for ELISA, WB, FACS, IF and ICC.

Quick Overview for HELLS antibody (AA 167-838) (ABIN7600237)

Target: HELLS (Helicase, Lymphoid-Specific (HELLS))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HELLS antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-HELLS Antibody

Binding Specificity: AA 167-838

Purpose: Anti-HELLS Antibody

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human HELLS shares 93% amino acid (aa) sequence identity with mouse HELLS.

Characteristics: Anti-HELLS Antibody. Tested in ELISA, IF, ICC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human HELLS recombinant protein (Position: N167-F838). Human HELLS shares 93% amino acid (aa) sequence identity with mouse HELLS.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for HELLS

Target: HELLS (Helicase, Lymphoid-Specific (HELLS))

Alternative Name: HELLS

Background:

Background: Lymphoid-specific helicase (Lsh) is a member of the SNF2 helicase family of chromatin remodeling proteins that in humans is encoded by the HELLS gene. This gene encodes a lymphoid-specific helicase. Other helicases function in processes involving DNA strand separation, including replication, repair, recombination, and transcription. This protein is thought to be involved with cellular proliferation and may play a role in leukemogenesis. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene Full Name: helicase, lymphoid specific

Molecular Weight: 97 kDa

Gene ID: 3070

UniProt: Q9NRZ9

Pathways: Chromatin Binding