STRIP2 antibody (AA 173-507)

Catalog No. ABIN7600294

The Rabbit Polyclonal anti-STRIP2 antibody is suitable to detect STRIP2 in samples from Human, Mouse and Rat. It has been validated for WB, IHC, ELISA and FACS.

Quick Overview for STRIP2 antibody (AA 173-507) (ABIN7600294)

Target: STRIP2 (Striatin Interacting Protein 2 (STRIP2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STRIP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Product Details anti-STRIP2 Antibody

Binding Specificity: AA 173-507

Purpose: Anti-FAM40B/STRIP2 Antibody

Predicted Reactivity: Human STRIP2 shares 96.4% amino acid (aa) sequence identity with mouse STRIP2.

Characteristics: Anti-FAM40B/STRIP2 Antibody. Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human FAM40B/STRIP2 recombinant protein (Position: H173-Q507). Human STRIP2 shares 96.4% amino acid (aa) sequence identity with mouse STRIP2.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for STRIP2

Target: STRIP2 (Striatin Interacting Protein 2 (STRIP2))

Alternative Name: STRIP2

Background:

Background: The STRIP2 gene encodes a protein known as striatin-interacting protein 2, which interacts with striatin, a scaffolding protein involved in diverse cellular processes such as signaling, cell adhesion, and transcriptional regulation. STRIP2 is implicated in cardiac development and function, where it modulates cardiac hypertrophy, contractility, and arrhythmogenesis. Additionally, it plays roles in neuronal development and synaptic plasticity in the brain. Dysregulation of STRIP2 expression or function has been associated with various cardiovascular disorders, including hypertrophic cardiomyopathy and arrhythmias, as well as neurodevelopmental disorders such as autism spectrum disorders. Elucidating the molecular mechanisms underlying STRIP2 function is essential for understanding its physiological roles in cardiac and neural tissues and its potential implications for disease pathology and therapeutic targeting.

Gene Full Name: striatin interacting protein 2

Molecular Weight: 100 kDa

Gene ID: 57464

UniProt: Q9ULQ0