ABR antibody (AA 180-859)

Catalog No. ABIN7600360

The Rabbit Polyclonal anti-ABR antibody is suitable to detect ABR in samples from Human, Mouse and Rat. It has been validated for ELISA, WB, IHC, FACS, ICC and IF.

Quick Overview for ABR antibody (AA 180-859) (ABIN7600360)

Target: ABR (Active BCR-Related (ABR))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABR antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-ABR Antibody

Binding Specificity: AA 180-859

Purpose: Anti-ABR Antibody

Predicted Reactivity: Human ABR shares 99.3% amino acid (aa) sequence identity with both mouse,rat ABR.

Characteristics: Anti-ABR Antibody. Tested in WB, IHC, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human ABR recombinant protein (Position: Q180-V859). Human ABR shares 99.3% amino acid (aa) sequence identity with both mouse and rat ABR.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ABR

Target: ABR (Active BCR-Related (ABR))

Alternative Name: ABR

Background:

Background: This gene encodes a protein that is similar to the protein encoded by the breakpoint cluster region gene located on chromosome 22. The protein encoded by this gene contains a GTPase-activating protein domain, a domain found in members of the Rho family of GTP-binding proteins. Functional studies in mice determined that this protein plays a role in vestibular morphogenesis. Alternatively spliced transcript variants have been reported for this gene.

Gene Full Name: ABR activator of RhoGEF and GTPase

Molecular Weight: 100 kDa

Gene ID: 29

UniProt: Q12979

Pathways: Neurotrophin Signaling Pathway, Regulation of Leukocyte Mediated Immunity