KIF2A antibody (AA 2-706)

Catalog No. ABIN7600510

The Rabbit Polyclonal anti-KIF2A antibody has been validated for ELISA, WB, IHC, IF, ICC and FACS. It is suitable to detect KIF2A in samples from Human, Mouse, Rat and Monkey.

Quick Overview for KIF2A antibody (AA 2-706) (ABIN7600510)

Target: KIF2A (Kinesin Heavy Chain Member 2A (KIF2A))

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KIF2A antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Product Details anti-KIF2A Antibody

Binding Specificity: AA 2-706

Purpose: Anti-KIF2A Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-KIF2A Antibody Picoband® (ABIN7600510). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat, Monkey. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human KIF2A recombinant protein (Position: A2-L706).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat, Monkey
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Debernardi, S., Fontanella, E., De Gregorio, L., Pierotti, M. A., Delia, D. Identification of a novel human kinesin-related gene (HK2) by the cDNA differential display technique. Genomics 42: 67-73, 1997. 2. Gross, M. B. Personal Communication. Baltimore, Md. 9/18/2013. 3. Homma, N., Takei, Y., Tanaka, Y., Nakata, T., Terada, S., Kikkawa, M., Noda, Y., Hirokawa, N. Kinesin superfamily protein 2A (KIF2A) functions in suppression of collateral branch extension. Cell 114: 229-239, 2003.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for KIF2A

Target: KIF2A (Kinesin Heavy Chain Member 2A (KIF2A))

Alternative Name: KIF2A

Background:

Synonyms: Intercellular adhesion molecule 2, ICAM-2, CD102, ICAM2

Tissue Specificity: Highly expressed in lung. Also detected in pancreas, kidney, small intestine, ovary, testis, prostate and mammary gland. In lung, it is found in alveolar type II cells but not in bronchiolar epithelium.

Background: Kinesin-like protein KIF2A is a protein that in humans is encoded by the KIF2A gene. The protein encoded by this gene is a plus end-ed motor required for normal mitotic progression. The encoded protein is required for normal spindle activity during mitosis and is necessary for normal brain development. Several transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 110 kDa

Gene ID: 3796

UniProt: O00139

Pathways: Microtubule Dynamics, Ribonucleoprotein Complex Subunit Organization