SCYL2 antibody (AA 208-909)

Catalog No. ABIN7600588

The Rabbit Polyclonal anti-SCYL2 antibody is suitable to detect SCYL2 in samples from Human. It has been validated for WB, ELISA, IF, FACS and ICC.

Quick Overview for SCYL2 antibody (AA 208-909) (ABIN7600588)

Target: SCYL2 (SCY1-Like 2 (SCYL2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCYL2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Product Details anti-SCYL2 Antibody

Binding Specificity: AA 208-909

Purpose: Anti-SCYL2 Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-SCYL2 Antibody. Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SCYL2 recombinant protein (Position: E208-Q909).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SCYL2

Target: SCYL2 (SCY1-Like 2 (SCYL2))

Alternative Name: SCYL2

Background:

Background: SCY1-like protein 2 is a protein that in humans is encoded by the SCYL2 gene. The protein encoded by this gene associates with clathrin-coated complexes at the plasma membrane and with endocytic coated vesicles. The encoded protein phosphorylates the beta2 subunit of the plasma membrane adapter complex AP2 and interacts with clathrin, showing involvement in clathrin-dependent pathways between the trans-Golgi network and the endosomal system. In addition, this protein has a role in the Wnt signaling pathway by targeting frizzled 5 (Fzd5) for lysosomal degradation. Two transcript variants encoding the same protein have been found for this gene.

Gene Full Name: SCY1 like pseudokinase 2

Molecular Weight: 104 kDa

Gene ID: 55681

UniProt: Q6P3W7