TUBGCP2 antibody (AA 213-888)

Catalog No. ABIN7600646

Product Details anti-TUBGCP2 Antibody

Target: TUBGCP2 (Tubulin, gamma Complex Associated Protein 2 (TUBGCP2))

Binding Specificity: AA 213-888

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TUBGCP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Purpose: Anti-TUBGCP2 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-TUBGCP2 Antibody Picoband® (ABIN7600646). Tested in ELISA, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TUBGCP2 recombinant protein (Position: Q213-R888).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Hartz, P. A. Personal Communication. Baltimore, Md. 12/18/2017. 2. Mitani, T., Punetha, J., Akalin, I., Pehlivan, D., Dawidziuk, M., Akdemir, Z. C., Yilmaz, S., Aslan, E., Hunter, J. V., Hijazi, H., Grochowski, C. M., Jhangiani, S. N., and 25 others. Bi-allelic pathogenic variants in TUBGCP2 cause microcephaly and lissencephaly spectrum disorders. Am. J. Hum. Genet. 105: 1005-1015, 2019. 3. Murphy, S. M., Urbani, L., Stearns, T. The mammalian gamma-tubulin complex contains homologues of the yeast spindle pole body components Spc97p and Spc98p. J. Cell Biol. 141: 663-674, 1998.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for TUBGCP2

Target: TUBGCP2 (Tubulin, gamma Complex Associated Protein 2 (TUBGCP2))

Alternative Name: TUBGCP2 (TUBGCP2 Products)

Background:

Synonyms: Neutrophil defensin 1,Defensin, alpha 1,HNP-1,HP-1,HP1,HP 1-56,Neutrophil defensin 2,HNP-2,HP-2,HP2,DEFA1,DEF1, DEFA2, MRS,DEFA1B,

Tissue Specificity: Expressed in immature but not mature T-cells. Also found in CD34+ cells from peripheral blood, CD34+ precursors from umbilical cord blood and adult bone marrow.

Background: Gamma-tubulin complex component 2 is a protein that in humans is encoded by the TUBGCP2 gene. It is part of the gamma tubulin complex, which required formicrotubule nucleation at the centrosome. Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome. Gamma-tubulin complex is composed of gamma-tubulin, TUBGCP2, TUBGCP3, TUBGCP4, TUBGCP5 and TUBGCP6.

Molecular Weight: 103 kDa

Gene ID: 10844

Pathways: M Phase, SARS-CoV-2 Protein Interactome