CHIA antibody (AA 228-476)

Catalog No. ABIN7600726

The Rabbit Polyclonal anti-CHIA antibody has been validated for WB, ELISA and FACS. It is suitable to detect CHIA in samples from Human, Mouse and Rat.

Quick Overview for CHIA antibody (AA 228-476) (ABIN7600726)

Target: CHIA (Chitinase, Acidic (CHIA))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHIA antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-CHIA Antibody

Binding Specificity: AA 228-476

Purpose: Anti-AMCase/CHIA Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-AMCase/CHIA Antibody Picoband® (ABIN7600726). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human AMCase/CHIA recombinant protein (Position: L228-A476).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.5-1 μg/mL, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Boot, R. G., Blommaart, E. F. C., Swart, E., Ghauharali-van der Vlugt, K., Bijl, N., Moe, C., Place, A., Aerts, J. M. F. G. Identification of a novel acidic mammalian chitinase distinct from chitotriosidase. J. Biol. Chem. 276: 6770-6778, 2001. 2. Reese, T. A., Liang, H.-E., Tager, A. M., Luster, A. D., Van Rooijen, N., Voehringer, D., Locksley, R. M. Chitin induces accumulation in tissue of innate immune cells associated with allergy. Nature 447: 92-96, 2007. 3. Saito, A., Ozaki, K., Fujiwara, T., Nakamura, Y., Tanigami, A. Isolation and mapping of a human lung-specific gene, TSA1902, encoding a novel chitinase family member. Gene 239: 325-331, 1999.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for CHIA

Target: CHIA (Chitinase, Acidic (CHIA))

Alternative Name: CHIA

Background:

Synonyms: Insulin-like growth factor-binding protein 3, IBP-3, IGF-binding protein 3, IGFBP-3, Igfbp3, Igfbp-3,

Background: The protein encoded by this gene degrades chitin, which is found in the cell wall of most fungi as well as in arthropods and some nematodes. The encoded protein can also stimulate interleukin 13 expression, and variations in this gene can lead to asthma susceptibility. Several transcript variants encoding a few different isoforms have been found for this gene.

Molecular Weight: 55 kDa

Gene ID: 27159