Myosin IB antibody (AA 231-1125)

Catalog No. ABIN7600775

Product Details anti-Myosin IB Antibody

Target: Myosin IB (MYO1B)

Binding Specificity: AA 231-1125

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Myosin IB antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Purpose: Anti-MYO1B Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-MYO1B Antibody Picoband® (ABIN7600775). Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human MYO1B recombinant protein (Position: R231-R1125).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bement, W. M., Hasson, T., Wirth, J. A., Cheney, R. E., Mooseker, M. S. Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types. Proc. Nat. Acad. Sci. 91: 6549-6553, 1994. Note: Erratum: Proc. Nat. Acad. Sci. 91: 11767 only, 1994.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for Myosin IB

Target: Myosin IB (MYO1B)

Alternative Name: MYO1B (MYO1B Products)

Background:

Synonyms: Aflatoxin B1 aldehyde reductase member 2, AFB1 aldehyde reductase 1, AFB1-AR 1, Aldoketoreductase 7, Succinic semialdehyde reductase, SSA reductase, AKR7A2, AFAR, AFAR1, AKR7

Tissue Specificity: Expressed in basement membranes of lung and kidney. Muscle- and neuron-specific isoforms are found. Isoforms (y+) with the 4 AA insert and (z+8) isoforms with the 8 AA insert are all neuron-specific. Isoforms (z+11) are found in both neuronal and non-neuronal tissues.

Background: Myosin-Ib is a protein that in humans is encoded by the MYO1B gene. Enables ATP binding activity, actin filament binding activity, and microfilament motor activity. Involved in actin filament organization and post-Golgi vesicle-mediated transport. Located in several cellular components, including actin filament, endosome, and perinuclear region of cytoplasm. Colocalizes with trans-Golgi network membrane.

Molecular Weight: 124 kDa

Gene ID: 4430

UniProt: O43795