TIMD4 antibody (AA 24-378)

Catalog No. ABIN7600827

This Rabbit Polyclonal antibody specifically detects TIMD4 in ELISA and WB. It exhibits reactivity toward Human.

Quick Overview for TIMD4 antibody (AA 24-378) (ABIN7600827)

Target: TIMD4 (T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TIMD4 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-TIMD4 Antibody

Binding Specificity: AA 24-378

Purpose: Anti-TIM 4/TIMD4 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-TIM 4/TIMD4 Antibody Picoband® (ABIN7600827). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TIM 4/TIMD4 recombinant protein (Position: S24-L378).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Czuczman, M. A., Fattouh, R., van Rijn, J. M., Canadien, V., Osborne, S., Muise, A. M., Kuchroo, V. K., Higgins, D. E., Brumell, J. H. Listeria monocytogenes exploits efferocytosis to promote cell-to-cell spread. Nature 509: 230-234, 2014. 2. Kuchroo, V. K., Umetsu, D. T., DeKruyff, R. H., Freeman, G. J. The TIM gene family: emerging roles in immunity and disease. Nature Rev. Immun. 3: 454-462, 2003. 3. Meyers, J. H., Chakravarti, S., Schlesinger, D., Illes, Z., Waldner, H., Umetsu, S. E., Kenny, J., Zheng, X. X., Umetsu, D. T., DeKruyff, R. H., Strom, T. B., Kuchroo, V. K. TIM-4 is the ligand for TIM-1, and the TIM-1-TIM-4 interaction regulates T cell proliferation. Nature Immun. 6: 455-464, 2005.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for TIMD4

Target: TIMD4 (T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4))

Alternative Name: TIMD4

Background:

Synonyms: Pancreatic secretory granule membrane major glycoprotein GP2, Pancreatic zymogen granule membrane protein GP-2, Gp2

Tissue Specificity: Expressed in all tissues tested including, liver, heart, adipose tissue, mammary gland, testes, ovary, brain, kidney and muscle. Highest levels in liver.

Background: T-cell immunoglobulin and mucin domain containing 4 (TIMD-4) also known as T-cell membrane protein 4 (TIM-4) is a protein in humans that is encoded by the TIMD4 gene.

Molecular Weight: 42 kDa

Gene ID: 91937

UniProt: Q96H15

Pathways: Cancer Immune Checkpoints