SNRPA1 antibody (AA 25-218)

Catalog No. ABIN7600891

The Rabbit Polyclonal anti-SNRPA1 antibody has been validated for WB, ELISA, IHC, IF and ICC. It is suitable to detect SNRPA1 in samples from Human, Mouse and Rat.

Quick Overview for SNRPA1 antibody (AA 25-218) (ABIN7600891)

Target: SNRPA1 (SNRPA) (Small Nuclear Ribonucleoprotein Polypeptide A (SNRPA))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNRPA1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-SNRPA1 Antibody

Binding Specificity: AA 25-218

Purpose: Anti-U1A/SNRPA Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-U1A/SNRPA Antibody Picoband® (ABIN7600891). Tested in ELISA, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human U1A/SNRPA recombinant protein (Position: E25-E218).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Immunofluorescence, 5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Nelissen, R. L. H., Sillekens, P. T. G., Beijer, R. P., Geurts van Kessel, A. H. M., van Venrooij, W. J. Structure, chromosomal localization and evolutionary conservation of the gene encoding human U1 snRNP-specific A protein. Gene 102: 189-196, 1991. 2. Schonk, D., van Dijk, P., Riegmann, P., Trapman, J., Holm, C., Willcocks, T. C., Sillekens, P., van Venrooij, W., Wimmer, E., Geurts van Kessel, A., Ropers, H.-H., Wieringa, B. Assignment of seven genes to distinct intervals on the midportion of human chromosome 19q surrounding the myotonic dystrophy gene region. Cytogenet. Cell Genet. 54: 15-19, 1990. 3. Sillekens, P. T. G., Habets, W. J., Beijer, R. P., van Venrooij, W. J. cDNA cloning of the human U1 snRNA-associated A protein: extensive homology between U1 and U2 snRNP-specific proteins. EMBO J. 6: 3841-3848, 1987.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for SNRPA1

Target: SNRPA1 (SNRPA) (Small Nuclear Ribonucleoprotein Polypeptide A (SNRPA))

Alternative Name: SNRPA

Background:

Synonyms: Epidermal growth factor-like protein 6, EGF-like protein 6, MAM and EGF domains-containing gene protein, EGFL6, MAEG, PP648, UNQ281/PRO320

Tissue Specificity: Ubiquitous.

Background: U1 small nuclear ribonucleoprotein A is a protein that in humans is encoded by the SNRPA gene. The protein encoded by this gene associates with stem loop II of the U1 small nuclear ribonucleoprotein, which binds the 5' splice site of precursor mRNAs and is required for splicing. The encoded protein autoregulates itself by polyadenylation inhibition of its own pre-mRNA via dimerization and has been implicated in the coupling of splicing and polyadenylation.

Molecular Weight: 31 kDa

Gene ID: 6626

UniProt: P09012