Exonuclease 1 antibody (AA 25-846)

Catalog No. ABIN7600922

This anti-Exonuclease 1 antibody is a Rabbit Polyclonal antibody detecting Exonuclease 1 in WB, ELISA, IP, IF, ICC and FACS. Suitable for Human.

Quick Overview for Exonuclease 1 antibody (AA 25-846) (ABIN7600922)

Target: Exonuclease 1 (EXO1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Exonuclease 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Product Details anti-Exonuclease 1 Antibody

Binding Specificity: AA 25-846

Purpose: Anti-Exonuclease 1/EXO1 Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-Exonuclease 1/EXO1 Antibody (ABIN7600922). Tested in ELISA, IF, ICC, WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Exonuclease 1/EXO1 recombinant protein (Position: Q25-Q846).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Immunoprecipitation, 0.5-2 μg/mL, Human
Flow Cytometry(Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for Exonuclease 1

Target: Exonuclease 1 (EXO1)

Alternative Name: EXO1

Background:

Synonyms: Exodeoxyribonuclease 1, Exodeoxyribonuclease I, EXO I, Exonuclease I, Protein DHS1, EXO1, DHS1, YOR033C, OR26.23

Tissue Specificity: Highly expressed in bone marrow, testis and thymus. Expressed at lower levels in colon, lymph nodes, ovary, placenta, prostate, small intestine, spleen and stomach.

Background: Exonuclease 1is anenzymethat in humans is encoded by theEXO1gene. It is mapped to 1q43. This gene encodes a protein with 5' to 3' exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in mismatch repair and recombination. Alternative splicing of this gene results in three transcript variants encoding two different isoforms.

Molecular Weight: 120 kDa

Gene ID: 9156

Pathways: DNA Damage Repair, Production of Molecular Mediator of Immune Response