Endoglin antibody (AA 26-267)
Quick Overview for Endoglin antibody (AA 26-267) (ABIN7600952)
Target
See all Endoglin (ENG) AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Binding Specificity
- AA 26-267
-
Purpose
- Anti-CD105/ENG Antibody
-
Cross-Reactivity (Details)
- No cross-reactivity with other proteins.
-
Characteristics
- Anti-/ENG Antibody (ABIN7600952). Tested in ELISA, Flow Cytometry, IF, IHC, WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
-
Purification
- Immunogen affinity purified.
-
Immunogen
- E.coli-derived human CD105/ENG recombinant protein (Position: E26-H267).
-
Isotype
- IgG
-
-
-
-
Application Notes
-
Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
Concentration
- 500 μg/mL
-
Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
Storage
- 4 °C,-20 °C
-
Storage Comment
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- Endoglin (ENG)
-
Alternative Name
- ENG
-
Background
-
Synonyms: Endoglin, Cell surface MJ7/18 antigen, CD105, Eng, Edg,
Background: Endoglin (Osler-Rendu-Weber syndrome 1), CD105, is a type I membrane glycoprotein located on cell surfaces and is a part of the TGF beta receptor complex. Its gene is mapped to human chromosome 8. The protein consists of a homodimer of 180 kDA with disulfide links. It has been found on endothelial cells, activated macrophages, fibroblasts and smooth muscle cells. Endoglin has a role in the development of the cardiovascular system and in vascular remodeling and has been found to be elevated in pregnant women who subsequently develop preeclampsia.
-
Molecular Weight
- 95 kDa
-
Gene ID
- 2022
-
UniProt
- P17813
Target
-