SMOC1 antibody (AA 27-434)

Catalog No. ABIN7601016

This Rabbit Polyclonal antibody specifically detects SMOC1 in ELISA, WB and FACS. It exhibits reactivity toward Human.

Quick Overview for SMOC1 antibody (AA 27-434) (ABIN7601016)

Target: SMOC1 (SPARC Related Modular Calcium Binding 1 (SMOC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMOC1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-SMOC1 Antibody

Binding Specificity: AA 27-434

Purpose: Anti-SMOC1 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-SMOC1 Antibody Picoband® (ABIN7601016). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SMOC1 recombinant protein (Position: H27-V434).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Abouzeid, H., Boisset, G., Favez, T., Youssef, M., Marzouk, I., Shakankiry, N., Bayoumi, N., Descombes, P., Agosti, C., Munier, F. L., Schorderet, D. F. Mutations in the SPARC-related modular calcium-binding protein 1 gene, SMOC1, cause Waardenburg anophthalmia syndrome. Am. J. Hum. Genet. 88: 92-98, 2011. 2. Hamanoue, H., Megarbane, A., Tohma, T., Nishimura, A., Mizuguchi, T., Saitsu, H., Sakai, H., Miura, S., Toda, T., Miyake, N., Niikawa, N., Yoshiura, K., Hirahara, F., Matsumoto, N. A locus for ophthalmo-acromelic syndrome mapped to 10p11.23. Am. J. Med. Genet. 149A: 336-342, 2009. 3. Okada, I., Hamanoue, H., Terada, K., Tohma, T., Megarbane, A., Chouery, E., Abou-Ghoch, J., Jalkh, N., Cogulu, O., Ozkinay, F., Horie, K., Takeda, J., and 16 others. SMOC1 is essential for ocular and limb development in humans and mice. Am. J. Hum. Genet. 88: 30-41, 2011.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for SMOC1

Target: SMOC1 (SPARC Related Modular Calcium Binding 1 (SMOC1))

Alternative Name: SMOC1

Background:

Synonyms: Protein SOX-15, Protein SOX-12, Protein SOX-20, SOX15, SOX12, SOX20, SOX26, SOX27

Tissue Specificity: Widely expressed in fetal and adult tissues examined, highest level found in fetal spinal cord and adult brain and testis.

Background: This gene encodes a multi-domain secreted protein that may have a critical role in ocular and limb development. Mutations in this gene are associated with microphthalmia and limb anomalies. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 70 kDa

Gene ID: 64093

UniProt: Q9H4F8

Pathways: SARS-CoV-2 Protein Interactome