SPATA18 antibody (AA 27-490)

Catalog No. ABIN7601020

The Rabbit Polyclonal anti-SPATA18 antibody is suitable to detect SPATA18 in samples from Human. It has been validated for WB, ELISA, IHC and FACS.

Quick Overview for SPATA18 antibody (AA 27-490) (ABIN7601020)

Target: SPATA18 (Spermatogenesis Associated 18 (SPATA18))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPATA18 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Product Details anti-SPATA18 Antibody

Binding Specificity: AA 27-490

Purpose: Anti-SPATA18 Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-SPATA18 Antibody. Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SPATA18 recombinant protein (Position: E27-R490).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SPATA18

Target: SPATA18 (Spermatogenesis Associated 18 (SPATA18))

Alternative Name: SPATA18

Background:

Background: This gene encodes a p53-inducible protein that is able to induce lysosome-like organelles within mitochondria that eliminate oxidized mitochondrial proteins, thereby contributing to mitochondrial quality control. Dysregulation of mitochondrial quality control is associated with cancer and degenerative diseases. The encoded protein mediates accumulation of the lysosome-like mitochondrial organelles through interaction with B cell lymphoma 2 interacting protein 3 and B cell lymphoma 2 interacting protein 3 like at the outer mitochondrial membrane, which allows translocation of lysosomal proteins to the mitochondrial matrix from the cytosol. Alternative splicing results in multiple transcript variants.

Gene Full Name: spermatogenesis associated 18

Molecular Weight: 61 kDa

Gene ID: 132671

UniProt: Q8TC71