IRF7 antibody (AA 27-503)

Catalog No. ABIN7601022

This Rabbit Polyclonal antibody specifically detects IRF7 in WB, ELISA, IHC and FACS. It exhibits reactivity toward Human.

Quick Overview for IRF7 antibody (AA 27-503) (ABIN7601022)

Target: IRF7 (Interferon Regulatory Factor 7 (IRF7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRF7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Product Details anti-IRF7 Antibody

Binding Specificity: AA 27-503

Purpose: Anti-IRF7 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-IRF7 Antibody Picoband® (ABIN7601022). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human IRF7 recombinant protein (Position: Y27-A503).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Au, W.-C., Moore, P. A., LaFleur, D. W., Tombal, B., Pitha, P. M. Characterization of the interferon regulatory factor-7 and its potential role in the transcription activation of interferon A genes. J. Biol. Chem. 273: 29210-29217, 1998. 2. Au, W.-C., Yeow, W.-S., Pitha, P. M. Analysis of functional domain of interferon regulatory factor 7 and its association with IRF-3. Virology 280: 273-282, 2001. 3. Chen, H.-W., King, K., Tu, J., Sanchez, M., Luster, A. D., Shresta, S. The roles of IRF-3 and IRF-7 in innate antiviral immunity against Dengue virus. J. Immun. 191: 4194-4201, 2013.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for IRF7

Target: IRF7 (Interferon Regulatory Factor 7 (IRF7))

Alternative Name: IRF7

Background:

Synonyms: GTPase HRas,H-Ras-1,Ha-Ras,Transforming protein p21,c-H-ras,p21ras,GTPase HRas, N-terminally processed,HRAS,HRAS1,

Tissue Specificity: Widely expressed. .

Background: Interferon regulatory factor 7, also known as IRF7, is a member of the interferon regulatory factor family of transcription factors. This gene encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. It has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. Inducible expression of IRF7 is largely restricted to lymphoid tissue. The encoded protein plays an important role in the innate immune response against DNA and RNA viruses.

Molecular Weight: 70 kDa

Gene ID: 3665

UniProt: Q92985

Pathways: TLR Signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Autophagy