DLL4 antibody (AA 27-678)

Catalog No. ABIN7601029

The Rabbit Polyclonal anti-DLL4 antibody has been validated for WB, ELISA and FACS. It is suitable to detect DLL4 in samples from Human, Mouse and Rat.

Quick Overview for DLL4 antibody (AA 27-678) (ABIN7601029)

Target: DLL4 (delta-Like 4 (DLL4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DLL4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-DLL4 Antibody

Binding Specificity: AA 27-678

Purpose: Anti-DLL4 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-DLL4 Antibody Picoband® (ABIN7601029). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human DLL4 recombinant protein (Position: S27-E678).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. "Entrez Gene: DLL4 delta-like 4 (Drosophila)". 2. Dorsch M, Zheng G, Yowe D, et al. (2002). "Ectopic expression of Delta4 impairs hematopoietic development and leads to lymphoproliferative disease". Blood. 100 (6): 2046-55. 3. Shutter JR, Scully S, Fan W, Richards WG, Kitajewski J, Deblandre GA, Kintner CR, Stark KL (Jul 2000). "Dll4, a novel Notch ligand expressed in arterial endothelium". Genes Dev. 14 (11): 1313-8.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for DLL4

Target: DLL4 (delta-Like 4 (DLL4))

Alternative Name: DLL4

Background:

Synonyms: NF-kappa-B essential modulator,NEMO,FIP-3,IkB kinase-associated protein 1,IKKAP1,Inhibitor of nuclear factor kappa-B kinase subunit gamma,I-kappa-B kinase subunit gamma,IKK-gamma,IKKG,IkB kinase subunit gamma,NF-kappa-B essential modifier,IKBKG,FIP3, NEMO,

Tissue Specificity: Heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

Background: Delta-like 4 is a protein that in humans is encoded by the DLL4 gene. It is mapped to 15q15.1. This gene is a homolog of the Drosophila delta gene. The delta gene family encodes Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. And this gene plays an important role in promoting Th17 effector activity during mycobacterial challenge.

Molecular Weight: 80 kDa

Gene ID: 54567

Pathways: Notch Signaling