CEP135 antibody (AA 28-1034)

Catalog No. ABIN7601061

This Rabbit Polyclonal antibody specifically detects CEP135 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CEP135 antibody (AA 28-1034) (ABIN7601061)

Target: CEP135 (Centrosomal Protein 135kDa (CEP135))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CEP135 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CEP135 Antibody

Binding Specificity: AA 28-1034

Purpose: Anti-CEP135 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-C Antibody Picoband® (ABIN7601061). Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human CEP135 recombinant protein (Position: E28-E1034). Human CEP135 shares 82.8% amino acid (aa) sequence identity with mouse CEP135.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL
1. Andersen, J. S., Wilkinson, C. J., Mayor, T., Mortensen, P., Nigg, E. A., Mann, M. Proteomic characterization of the human centrosome by protein correlation profiling. Nature 426: 570-574, 2003. 2. Carvalho-Santos, Z., Machado, P., Branco, P., Tavares-Cadete, F., Rodrigues-Martins, A., Pereira-Leal, J. B., Bettencourt-Dias, M. Stepwise evolution of the centriole-assembly pathway. J. Cell Sci. 123: 1414-1426, 2010. 3. Farooq, M., Fatima, A., Mang, Y., Hansen, L., Kjaer, K. W., Baig, S. M., Larsen, L. A., Tommerup, N. A novel splice site mutation in CEP135 is associated with primary microcephaly in a Pakistani family. J. Hum. Genet. 61: 271-273, 2016.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for CEP135

Target: CEP135 (Centrosomal Protein 135kDa (CEP135))

Alternative Name: CEP135

Background:

Synonyms: CEP135, CEP4, KIAA0635, Centrosomal protein of 135 kDa, Cep135, Centrosomal protein 4

Background: Centrosomal protein of 135 kDa is a protein that in humans is encoded by the CEP135 gene. This gene encodes a centrosomal protein, which acts as a scaffolding protein during early centriole biogenesis, and is also required for centriole-centriole cohesion during interphase. Mutations in this gene are associated with autosomal recessive primary microcephaly-8.

Molecular Weight: 133 kDa

Gene ID: 9662

Pathways: M Phase, SARS-CoV-2 Protein Interactome