Importin 9 antibody (AA 37-1041)

Catalog No. ABIN7601492

This anti-Importin 9 antibody is a Rabbit Polyclonal antibody detecting Importin 9 in WB, ELISA, IHC and FACS. Suitable for Human, Mouse and Rat.

Quick Overview for Importin 9 antibody (AA 37-1041) (ABIN7601492)

Target: Importin 9 (IPO9)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Importin 9 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Product Details anti-Importin 9 Antibody

Binding Specificity: AA 37-1041

Purpose: Anti-IPO9 Antibody Picoband®

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Anti-IPO9 Antibody Picoband® (ABIN7601492). Tested in ELISA, IHC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human IPO9 recombinant protein (Position: Q37-I1041). Human IPO9 shares 99% amino acid (aa) sequence identity with mouse IPO9.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry, 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Clemons, A. M., Brockway, H. M., Yin, Y., Kasinathan, B., Butterfield, Y. S., Jones, S. J. M., Colaiacovo, M. P., Smolikove, S. akirin is required for diakinesis bivalent structure and synaptonemal complex disassembly at meiotic prophase I. Molec. Biol. Cell 24: 1053-1067, 2013. 2. de Almeida, M., Hinterndorfer, M., Brunner, H., Grishkovskaya, I., Singh, K., Schleiffer, A., Jude, J., Deswal, S., Kalis, R., Vunjak, M., Lendl, T., Imre, R., Roitinger, E., Neumann, T., Kandolf, S., Schutzbier, M., Mechtler, K., Versteeg, G. A., Haselbach, D., Zuber, J. AKIRIN2 controls the nuclear import of proteasomes in vertebrates. Nature 599: 491-496, 2021. 3. Goto, A., Matsushita, K., Gesellchen, V., El Chamy, L., Kuttenkeuler, D., Takeuchi, O., Hoffmann, J. A., Akira, S., Boutros, M., Reichhart, J.-M. Akirins are highly conserved nuclear proteins required for NF-kappa-B-dependent gene expression in drosophila and mice. Nature Immun. 9: 97-104, 2008. Note: Erratum: Nature Immun. 9: 216 only, 2008.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for Importin 9

Target: Importin 9 (IPO9)

Alternative Name: IPO9

Background:

Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody

Tissue Specificity: Expressed in all tissues.

Background: Importin-9 is a protein that in humans is encoded by the IPO9 gene. This gene encodes a protein that binds RAN, a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex. The protein encoded by this gene has also been shown to interact with several other proteins, including met proto-oncogene, homeodomain interacting protein kinase 2, androgen receptor, and cyclin-dependent kinase 11.

Molecular Weight: 120 kDa

Gene ID: 55705

UniProt: Q96P70

Pathways: Protein targeting to Nucleus