KDM6A antibody (AA 391-704)

Catalog No. ABIN7601589

This Rabbit Polyclonal antibody specifically detects KDM6A in WB, ELISA, FACS, IF and ICC. It exhibits reactivity toward Human.

Quick Overview for KDM6A antibody (AA 391-704) (ABIN7601589)

Target: KDM6A (Lysine (K)-Specific Demethylase 6A (KDM6A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KDM6A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-KDM6A Antibody

Binding Specificity: AA 391-704

Purpose: Anti-UTX/KDM6A Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-UTX/KDM6A Antibody. Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human UTX/KDM6A recombinant protein (Position: A391-A704).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for KDM6A

Target: KDM6A (Lysine (K)-Specific Demethylase 6A (KDM6A))

Alternative Name: KDM6A

Background:

Background: Lysine-specific demethylase 6A also known as Ubiquitously transcribed tetratricopeptide repeat, X chromosome (UTX), is a protein which in humans is encoded by the KDM6A gene. This gene is located on the X chromosome and is the corresponding locus to a Y-linked gene which encodes a tetratricopeptide repeat (TPR) protein. The encoded protein of this gene contains a JmjC-domain and catalyzes the demethylation of tri/dimethylated histone H3. Multiple alternatively spliced transcript variants have been found for this gene.

Gene Full Name: lysine demethylase 6A

Molecular Weight: 154 kDa

Gene ID: 7403

UniProt: O15550

Pathways: Tube Formation, Warburg Effect