JMJD5 antibody (AA 4-406)

Catalog No. ABIN7601624

This anti-JMJD5 antibody is a Rabbit Polyclonal antibody detecting JMJD5 in WB and ELISA. Suitable for Human.

Quick Overview for JMJD5 antibody (AA 4-406) (ABIN7601624)

Target: JMJD5 (Jumonji Domain Containing 5 (JMJD5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JMJD5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-JMJD5 Antibody

Binding Specificity: AA 4-406

Purpose: Anti-KDM8 Antibody Picoband®

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Anti-KDM8 Antibody Picoband® (ABIN7602112). Tested in WB, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human KDM8 recombinant protein (Position: D4-D406). Human KDM8 shares 78.1% and 78.9% amino acid (aa) sequence identity with mouse and rat KDM8, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Hartz, P. A. Personal Communication. Baltimore, Md. 3/17/2008. 2. Marcon, E., Ni, Z., Pu, S., Turinsky, A. L., Trimble, S. S., Olsen, J. B., Silverman-Gavrila, R., Silverman-Gavrila, L., Phanse, S., Guo, H., Zhong, G., Guo, X., and 13 others. Human-chromatin-related protein interactions identify a demethylase complex required for chromosome segregation. Cell. Rep. 8: 297-310, 2014. 3. Shi, Y. Histone lysine demethylases: emerging roles in development, physiology and disease. Nature Rev. Genet. 8: 829-833, 2007.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for JMJD5

Target: JMJD5 (Jumonji Domain Containing 5 (JMJD5))

Alternative Name: KDM8

Background:

Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody

Tissue Specificity: Expressed in all tissues.

Background: Lysine demethylase 8 is a protein that in humans is encoded by the KDM8 gene. This gene likely encodes a histone lysine demethylase. Studies of a similar protein in mouse indicate a potential role for this protein as a tumor suppressor. Alternatively spliced transcript variants have been described.

Molecular Weight: 55 kDa

Gene ID: 79831

UniProt: Q8N371

Pathways: Chromatin Binding