SLU7 antibody (AA 42-474)

Catalog No. ABIN7601697

This Rabbit Polyclonal antibody specifically detects SLU7 in WB, ELISA, IHC, IF, ICC and FACS. It exhibits reactivity toward Human.

Quick Overview for SLU7 antibody (AA 42-474) (ABIN7601697)

Target: SLU7 (SLU7 Splicing Factor Homolog (SLU7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLU7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Product Details anti-SLU7 Antibody

Binding Specificity: AA 42-474

Purpose: Anti-SLU7 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-SLU7 Antibody Picoband® (ABIN7601697). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SLU7 recombinant protein (Position: Q42-I474).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10^6 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Chua, K., Reed, R. Human step II splicing factor hSlu7 functions in restructuring the spliceosome between the catalytic steps of splicing. Genes Dev. 13: 841-850, 1999. 2. Chua, K., Reed, R. The RNA splicing factor hSlu7 is required for correct 3-prime splice-site choice. Nature 402: 207-210, 1999. 3. Lev-Maor, G., Sorek, R., Shomron, N., Ast, G. The birth of an alternatively spliced exon: 3-prime splice-site selection in Alu exons. Science 300: 1288-1291, 2003.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for SLU7

Target: SLU7 (SLU7 Splicing Factor Homolog (SLU7))

Alternative Name: SLU7

Target Type: Influenza Protein

Background:

Synonyms: C-C motif chemokine 16, Chemokine CC-4, HCC-4, Chemokine LEC, IL-10-inducible chemokine, LCC-1, Liver-expressed chemokine, Lymphocyte and monocyte chemoattractant, LMC, Monotactin-1, MTN-1, NCC-4, Small-inducible cytokine A16, CCL16, ILINCK, NCC4, SCYA16

Tissue Specificity: Mainly expressed in liver, also found in spleen and thymus. Highly expressed in LPS- and IFN-gamma- activated monocytes, weakly in some lymphocytes, including natural killer cells, gamma-delta T-cells, and some T-cell clones.

Background: Pre-mRNA-splicing factor SLU7 is a protein that in humans is encoded by the SLU7 gene. Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is a splicing factor that has been found to be essential during the second catalytic step in the pre-mRNA splicing process. It associates with the spliceosome and contains a zinc knuckle motif that is found in other splicing factors and is involved in protein-nucleic acid and protein-protein interactions.

Molecular Weight: 68 kDa

Gene ID: 10569

UniProt: O95391

Pathways: Ribonucleoprotein Complex Subunit Organization, SARS-CoV-2 Protein Interactome