Plexin C1 antibody (AA 420-819)

Catalog No. ABIN7601703

This Rabbit Polyclonal antibody specifically detects Plexin C1 in ELISA, WB and FACS. It exhibits reactivity toward Human.

Quick Overview for Plexin C1 antibody (AA 420-819) (ABIN7601703)

Target: Plexin C1 (PLXNC1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Plexin C1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-Plexin C1 Antibody

Binding Specificity: AA 420-819

Purpose: Anti-PLXNC1 Antibody Picoband®

Characteristics: Anti-PLXNC1 Antibody Picoband® (ABIN7601703). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PLXNC1 recombinant protein (Position: K420-R819). Human PLXNC1 shares 78.6% amino acid (aa) sequence identity with mouse PLXNC1.

Application Details

Application Notes: Western blot, 0.1-0.25 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg /1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Comeau, M. R., Johnson, R., DuBose, R. F., Petersen, M., Gearing, P., VandenBos, T., Park, L., Farrah, T., Buller, R. M., Cohen, J. I., Stockbine, L. D., Rauch, C., Spriggs, M. K. A poxvirus-encoded semaphorin induces cytokine production from monocytes and binds to a novel cellular semaphorin receptor, VESPR. Immunity 8: 473-482, 1998. 2. Tamagnone, L., Artigiani, S., Chen, H., He, Z., Ming, G., Song, H., Chedotal, A., Winberg, M. L., Goodman, C. S., Poo, M., Tessier-Lavigne, M., Comoglio, P. M. Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates. Cell 99: 71-80, 1999. Note: Erratum: Cell 104: following 320, 2001.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for Plexin C1

Target: Plexin C1 (PLXNC1)

Alternative Name: PLXNC1

Background: This gene encodes a member of the plexin family. Plexins are transmembrane receptors for semaphorins, a large family of proteins that regulate axon guidance, cell motility and migration, and the immune response. The encoded protein and its ligand regulate melanocyte adhesion, and viral semaphorins may modulate the immune response by binding to this receptor. The encoded protein may be a tumor suppressor protein for melanoma. Alternatively spliced transcript variants have been observed for this gene.

Molecular Weight: 220 kDa

Gene ID: 10154

UniProt: O60486