FAM105B antibody (AA 49-352)

Catalog No. ABIN7601854

The Rabbit Polyclonal anti-FAM105B antibody is suitable to detect FAM105B in samples from Human, Mouse and Rat. It has been validated for WB, FACS, ELISA, IHC, IF and ICC.

Quick Overview for FAM105B antibody (AA 49-352) (ABIN7601854)

Target: FAM105B (Family with Sequence Similarity 105, Member B (FAM105B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAM105B antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-FAM105B Antibody

Binding Specificity: AA 49-352

Purpose: Anti-OTULIN Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-OTULIN Antibody. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human OTULIN recombinant protein (Position: A49-L352).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for FAM105B

Target: FAM105B (Family with Sequence Similarity 105, Member B (FAM105B))

Alternative Name: OTULIN

Background:

Background: This gene encodes a member of the peptidase C65 family of ubiquitin isopeptidases. Members of this family remove ubiquitin from proteins. The encoded enzyme specifically recognizes and removes M1 (Met1)-linked, or linear, ubiquitin chains from protein substrates. Linear ubiquitin chains are known to regulate the NF-kappa B signaling pathway in the context of immunity and inflammation. Mutations in this gene cause a potentially fatal autoinflammatory syndrome in human patients.

Gene Full Name: OTU deubiquitinase with linear linkage specificity

Molecular Weight: 43-45 kDa

Gene ID: 90268

UniProt: Q96BN8