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Glycogen Synthase 1 antibody (AA 60-640)

This anti-Glycogen Synthase 1 antibody is a Rabbit Polyclonal antibody detecting Glycogen Synthase 1 in WB, ELISA, IHC, IF, ICC and FACS. Suitable for Human, Mouse and Rat.
Catalog No. ABIN7602155

Quick Overview for Glycogen Synthase 1 antibody (AA 60-640) (ABIN7602155)

Target

See all Glycogen Synthase 1 (GYS1) Antibodies
Glycogen Synthase 1 (GYS1) (Glycogen Synthase 1 (Muscle) (GYS1))

Reactivity

  • 62
  • 38
  • 30
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Human, Mouse, Rat

Host

  • 61
  • 2
Rabbit

Clonality

  • 46
  • 17
Polyclonal

Conjugate

  • 42
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
This Glycogen Synthase 1 antibody is un-conjugated

Application

  • 42
  • 27
  • 16
  • 11
  • 9
  • 7
  • 6
  • 4
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)
  • Binding Specificity

    • 18
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 60-640

    Purpose

    Anti-Glycogen synthase 1/GYS1 Antibody Picoband®

    Cross-Reactivity (Details)

    No cross-reactivity with other proteins.

    Characteristics

    Anti-Glycogen synthase 1/GYS1 Antibody Picoband® (ABIN7602155). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Purification

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human Glycogen synthase 1/GYS1 recombinant protein (Position: D60-A640).

    Isotype

    IgG
  • Application Notes

    Western blot, 0.1-0.25 μg/mL, Mouse, Rat
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Browner, M. F., Nakano, K., Bang, A. G., Fletterick, R. J. Human muscle glycogen synthase cDNA sequence: a negatively charged protein with an asymmetric charge distribution. Proc. Nat. Acad. Sci. 86: 1443-1447, 1989. 2. Cameron, J. M., Levandovskiy, V., MacKay, N., Utgikar, R., Ackerley, C., Chiasson, D., Halliday, W., Raiman, J., Robinson, B. H. Identification of a novel mutation in GYS1 (muscle-specific glycogen synthase) resulting in sudden cardiac that, that is diagnosable from skin fibroblasts. Molec. Genet. Metab. 98: 378-382, 2009. 3. Groop, L. C., Kankuri, M., Schalin-Jantti, C., Ekstrand, A., Nikula-Ijas, P., Widen, E., Kuismanen, E., Eriksson, J., Franssila-Kallunki, A., Saloranta, C., Koskimies, S. Association between polymorphism of the glycogen synthase gene and non-insulin-dependent diabetes mellitus. New Eng. J. Med. 328: 10-14, 1993. Note: Erratum: New Eng. J. Med. 328: 1136 only, 1993.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Concentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Storage

    4 °C,-20 °C

    Storage Comment

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target

    Glycogen Synthase 1 (GYS1) (Glycogen Synthase 1 (Muscle) (GYS1))

    Alternative Name

    GYS1

    Background

    Synonyms: Rhombotin-2, Cysteine-rich protein TTG-2, LIM domain only protein 2, LMO-2, T-cell translocation protein 2, LMO2, RBTN2, RBTNL1, RHOM2, TTG2

    Background: Glycogen synthase (UDP-glucose-glycogen glucosyltransferase) is a key enzyme in glycogenesis, the conversion of glucose into glycogen. The protein encoded by this gene catalyzes the addition of glucose monomers to the growing glycogen molecule through the formation of alpha-1,4-glycoside linkages. Mutations in this gene are associated with muscle glycogen storage disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    Molecular Weight

    84-90 kDa

    Gene ID

    2997

    UniProt

    P13807

    Pathways

    PI3K-Akt Signaling, AMPK Signaling, Cellular Glucan Metabolic Process
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