Septin 12 antibody (AA 71-358)

Catalog No. ABIN7602363

This Rabbit Polyclonal antibody specifically detects Septin 12 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Septin 12 antibody (AA 71-358) (ABIN7602363)

Target: Septin 12 (Sep12)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Septin 12 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Septin 12 Antibody

Binding Specificity: AA 71-358

Purpose: Anti-SEPTIN12 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-SEPTIN12 Antibody Picoband® (ABIN7602363). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SEPTIN12 recombinant protein (Position: K71-F358).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Hall, P. A., Jung, K., Hillan, K. J., Russell, S. E. H. Expression profiling the human septin gene family. J. Path. 206: 269-278, 2005. 2. Kuo, Y.-C., Lin, Y.-H., Chen, H.-I., Wang, Y.-Y., Chiou, Y.-W., Lin, H.-H., Pan, H.-A., Wu, C.-M., Su, S.-M., Hsu, C.-C., Kuo, P.-L. SEPT12 mutations cause male infertility with defective sperm annulus. Hum. Mutat. 33: 710-719, 2012. 3. Lin, Y.-H., Chou, C.-K., Hung, Y.-C., Yu, I.-S., Pan, H.-A., Lin, S.-W., Kuo, P.-L. SEPT12 deficiency causes sperm nucleus damage and developmental arrest of preimplantation embryos. Fertil. Steril. 95: 363-365, 2011.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for Septin 12

Target: Septin 12 (Sep12)

Alternative Name: SEPTIN12

Background:

Synonyms: Mitochondrial import inner membrane translocase subunit Tim17-A, Inner membrane preprotein translocase Tim17a, TIMM17A, MIMT17, TIM17, TIM17A, TIMM17

Background: Septin 12 is a protein that in humans is encoded by the SEPT12 gene. This gene encodes a guanine-nucleotide binding protein and member of the septin family of cytoskeletal GTPases. Septins play important roles in cytokinesis, exocytosis, embryonic development, and membrane dynamics. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 45 kDa

Gene ID: 124404