ELP2 antibody (AA 84-826)

Catalog No. ABIN7602558

This Rabbit Polyclonal antibody specifically detects ELP2 in ELISA, WB, IF, FACS and ICC. It exhibits reactivity toward Human.

Quick Overview for ELP2 antibody (AA 84-826) (ABIN7602558)

Target: ELP2 (Elongator Acetyltransferase Complex Subunit 2 (ELP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ELP2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Product Details anti-ELP2 Antibody

Binding Specificity: AA 84-826

Purpose: Anti-ELP2 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-ELP2 Antibody Picoband® (ABIN7602558). Tested in WB, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human ELP2 recombinant protein (Position: D84-L826). Human ELP2 shares 77.9% and 79.8% amino acid (aa) sequence identity with mouse and rat ELP2, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL
1. Cohen, J. S., Srivastava, S., Farwell, K. D., Lu, H.-M., Zeng, W., Lu, H., Chao, E. C., Fatemi, A. ELP2 is a novel gene implicated in neurodevelopmental disabilities. Am. J. Med. Genet. 167A: 1391-1395, 2015. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 10/14/2014. 3. Hawkes, N. A., Otero, G., Winkler, G. S., Marshall, N., Dahmus, M. E., Krappmann, D., Scheidereit, C., Thomas, C. L., Schiavo, G., Erdjument-Bromage, H., Tempst, P., Svejstrup, J. Q. Purification and characterization of the human elongator complex. J. Biol. Chem. 277: 3047-3052, 2002.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for ELP2

Target: ELP2 (Elongator Acetyltransferase Complex Subunit 2 (ELP2))

Alternative Name: ELP2

Background:

Synonyms: ELP2, STATIP1, Elongator complex protein 2, ELP2, SHINC-2, STAT3-interacting protein 1, StIP1

Background: The protein encoded by this gene is a core subunit of the elongator complex, a histone acetyltransferase complex that associates with RNA polymerase II. In addition to histone acetylation, the encoded protein effects transcriptional elongation and may help remodel chromatin.

Molecular Weight: 93 kDa

Gene ID: 55250

Pathways: Stem Cell Maintenance, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus