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Fibronectin 1 antibody (AA 869-2014)

This Rabbit Polyclonal antibody specifically detects Fibronectin 1 in WB, ELISA and FACS. It exhibits reactivity toward Human.
Catalog No. ABIN7602579

Quick Overview for Fibronectin 1 antibody (AA 869-2014) (ABIN7602579)

Target

See all Fibronectin 1 (FN1) Antibodies
Fibronectin 1 (FN1)

Reactivity

  • 99
  • 36
  • 32
  • 9
  • 6
  • 6
  • 5
  • 5
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
Human

Host

  • 82
  • 31
  • 1
  • 1
Rabbit

Clonality

  • 77
  • 37
Polyclonal

Conjugate

  • 66
  • 15
  • 10
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Fibronectin 1 antibody is un-conjugated

Application

  • 73
  • 54
  • 29
  • 16
  • 13
  • 13
  • 13
  • 10
  • 10
  • 8
  • 7
  • 6
  • 6
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • Binding Specificity

    • 15
    • 8
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 869-2014

    Purpose

    Anti-Fibronectin/FN1 Antibody Picoband®

    Characteristics

    Anti-Fibronectin/FN1 Antibody Picoband® (ABIN7602579). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Purification

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human Fibronectin/FN1 recombinant protein (Position: D869-W2014). Human FN1 shares 91.2% and 91.4% amino acid (aa) sequence identity with mouse and rat FN1, respectively.
  • Application Notes

    Western blot, 0.25-0.5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg /1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Bing, D. H., Almeda, S., Isliker, H., Lahav, J., Hynes, R. O. Fibronectin binds to the C1q component of complement. Proc. Nat. Acad. Sci. 79: 4198-4201, 1982. 2. Castelletti, F., Donadelli, R., Banterla, F., Hildebrandt, F., Zipfel, P. F., Bresin, E., Otto, E., Skerka, C., Renieri, A., Todeschini, M., Caprioli, J., Caruso, M. R., Artuso, R., Remuzzi, G., Noris, M. Mutations in FN1 cause glomerulopathy with fibronectin deposits. Proc. Nat. Acad. Sci. 105: 2538-2543, 2008.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Concentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Storage

    4 °C,-20 °C

    Storage Comment

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target

    Fibronectin 1 (FN1)

    Alternative Name

    FN1

    Background

    Fibronectin is a high-molecular weight glycoprotein of the extracellular matrix that binds to membrane-spanning receptor proteins called integrins. It is mapped to 2q35. This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. The encoded preproprotein is proteolytically processed to generate the mature protein. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants, at least one of which encodes an isoform that undergoes proteolytic processing. The full-length nature of some variants has not been determined.

    Molecular Weight

    272 kDa

    Gene ID

    2335

    UniProt

    P02751

    Pathways

    Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy
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