TROVE2 antibody (AA 88-419)

Catalog No. ABIN7602595

The Rabbit Polyclonal anti-TROVE2 antibody has been validated for WB, ELISA and FACS. It is suitable to detect TROVE2 in samples from Human and Rat.

Quick Overview for TROVE2 antibody (AA 88-419) (ABIN7602595)

Target: TROVE2 (TROVE Domain Family, Member 2 (TROVE2))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TROVE2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-TROVE2 Antibody

Binding Specificity: AA 88-419

Purpose: Anti-TROVE2/SS-A/RO60 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-TROVE2/SS-A/RO60 Antibody Picoband® (ABIN7602595). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TROVE2/SS-A/RO60 recombinant protein (Position: K88-M419).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Alspaugh, M. A., Tan, E. M. Antibodies to cellular antigens in Sjogren's syndrome. J. Clin. Invest. 55: 1067-1073, 1975. 2. Ben-Chetrit, E., Gandy, B. J., Tan, E. M., Sullivan, K. F. Isolation and characterization of a cDNA clone encoding the 60-kD component of the human SS-A/Ro ribonucleoprotein autoantigen. J. Clin. Invest. 83: 1284-1292, 1989. 3. Chan, E. K. L., Tan, E. M., Ward, D. C., Matera, A. G. Human 60- kDa SS-A/Ro ribonucleoprotein autoantigen gene (SSA2) localized to 1q31 by fluorescence in situ hybridization. Genomics 23: 298-300, 1994.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for TROVE2

Target: TROVE2 (TROVE Domain Family, Member 2 (TROVE2))

Alternative Name: RO60

Background:

Synonyms: Vacuolar protein sorting-associated protein 4B, Cell migration-inducing gene 1 protein, Suppressor of K (+) transport growth defect 1, Protein SKD1, VPS4B, SKD1, VPS42, MIG1

Tissue Specificity: Ubiquitously expressed.

Background: Enables RNA binding activity. Involved in cellular response to interferon-alpha and regulation of gene expression. Located in cytosol and nucleoplasm. Part of ribonucleoprotein complex. The cDNA that encodes the 60-kD Ro/SSA autoantigen recognized by autoantibodies in certain lupus erythematosus (152700) and Sjogren syndrome (270150) sera was cloned and sequenced by Deutscher et al. (1988) and confirmed with minor differences by Ben-Chetrit et al. (1989).

Molecular Weight: 60 kDa

Gene ID: 6738

UniProt: P10155