Phospholipase C beta 1 antibody (AA 9-834)

Catalog No. ABIN7602641

The Rabbit Polyclonal anti-Phospholipase C beta 1 antibody (ABIN7602641) specifically detects Phospholipase C beta 1 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Phospholipase C beta 1 antibody (AA 9-834) (ABIN7602641)

Target: Phospholipase C beta 1 (PLCB1) (phospholipase C, beta 1 (phosphoinositide-Specific) (PLCB1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Phospholipase C beta 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Phospholipase C beta 1 Antibody

Binding Specificity: AA 9-834

Purpose: Anti-PLCB1 Antibody

Predicted Reactivity: Human PLCB1 shares 98.8%,98.5% amino acid (aa) sequence identity with mouse,rat PLCB1,respectively.

Characteristics: Anti-PLCB1 Antibody. Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PLCB1 recombinant protein (Position: H9-D834). Human PLCB1 shares 98.8% and 98.5% amino acid (aa) sequence identity with mouse and rat PLCB1, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Mouse, Rat ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Phospholipase C beta 1

Target: Phospholipase C beta 1 (PLCB1) (phospholipase C, beta 1 (phosphoinositide-Specific) (PLCB1))

Alternative Name: PLCB1

Background:

Background: PLCB1 is also known as PLC-I, EIEE12 or PLC154. The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: phospholipase C beta 1

Molecular Weight: 150 kDa

Gene ID: 23236

UniProt: Q9NQ66

Pathways: WNT Signaling, AMPK Signaling, Thyroid Hormone Synthesis, Inositol Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Proton Transport, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, G-protein mediated Events