MAG antibody (AA 501-582)

Catalog No. ABIN726920

The Rabbit Polyclonal anti-MAG antibody has been validated for WB, ELISA, IF (cc), IF (p), IHC (p) and IHC (fro). It is suitable to detect MAG in samples from Human, Mouse and Rat. There are 4+ publications available.

Quick Overview for MAG antibody (AA 501-582) (ABIN726920)

Target: MAG (Myelin Associated Glycoprotein (MAG))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAG antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-MAG Antibody

Binding Specificity: AA 501-582

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MAG

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-MAG antibody (ABIN726920)

Zhang, Gong, Qiu, Zhang, Gong: "MicroRNA-210 contributes to peripheral nerve regeneration through promoting the proliferation and migration of Schwann cells." in: Experimental and therapeutic medicine, Vol. 14, Issue 4, pp. 2809-2816, (2017) (PubMed).

Feng, Hao, Yang, Qu, Zheng, Liang, Jin et al.: "Transplantation of mesenchymal stem cells promotes the functional recovery of the central nervous system following cerebral ischemia by inhibiting myelin-associated inhibitor expression and neural ..." in: Experimental and therapeutic medicine, Vol. 11, Issue 5, pp. 1595-1600, (2016) (PubMed).

Ozgun-Acar, Celik-Turgut, Gazioglu, Kolak, Ozbal, Ergur, Arslan, Sen, Topcu: "Capparis ovata treatment suppresses inflammatory cytokine expression and ameliorates experimental allergic encephalomyelitis model of multiple sclerosis in C57BL/6 mice." in: Journal of neuroimmunology, Vol. 298, pp. 106-16, (2016) (PubMed).

Target Details for MAG

Target: MAG (Myelin Associated Glycoprotein (MAG))

Alternative Name: MAG

Background:

Synonyms: GMA, S-MAG, SIGLEC4A, SIGLEC-4A, Myelin-associated glycoprotein, MAG

Background: Adhesion molecule in postnatal neural development that mediates sialic-acid dependent cell-cell interactions between neuronal and myelinating cells. Preferentially binds to alpha-2,3-linked sialic acid (By similarity).

Gene ID: 4099

UniProt: P20916

Pathways: Neurotrophin Signaling Pathway