MAG antibody (AA 501-582)

Catalog No. ABIN726920

Product Details anti-MAG Antibody

Target: MAG (Myelin Associated Glycoprotein (MAG))

Binding Specificity: AA 501-582

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAG antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MAG

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-MAG antibody (ABIN726920)

Zhang, Gong, Qiu, Zhang, Gong: "MicroRNA-210 contributes to peripheral nerve regeneration through promoting the proliferation and migration of Schwann cells." in: Experimental and therapeutic medicine, Vol. 14, Issue 4, pp. 2809-2816, (2017) (PubMed).

Feng, Hao, Yang, Qu, Zheng, Liang, Jin et al.: "Transplantation of mesenchymal stem cells promotes the functional recovery of the central nervous system following cerebral ischemia by inhibiting myelin-associated inhibitor expression and neural ..." in: Experimental and therapeutic medicine, Vol. 11, Issue 5, pp. 1595-1600, (2016) (PubMed).

Ozgun-Acar, Celik-Turgut, Gazioglu, Kolak, Ozbal, Ergur, Arslan, Sen, Topcu: "Capparis ovata treatment suppresses inflammatory cytokine expression and ameliorates experimental allergic encephalomyelitis model of multiple sclerosis in C57BL/6 mice." in: Journal of neuroimmunology, Vol. 298, pp. 106-16, (2016) (PubMed).

Target Details for MAG

Target: MAG (Myelin Associated Glycoprotein (MAG))

Alternative Name: MAG (MAG Products)

Synonyms: GMA antibody, S-MAG antibody, SIGLEC-4A antibody, SIGLEC4A antibody, siglec-4 antibody, MAG antibody, Gma antibody, siglec-4a antibody, myelin associated glycoprotein antibody, myelin-associated glycoprotein antibody, MAG antibody, mag antibody, Mag antibody

Background:

Synonyms: GMA, S-MAG, SIGLEC4A, SIGLEC-4A, Myelin-associated glycoprotein, MAG

Background: Adhesion molecule in postnatal neural development that mediates sialic-acid dependent cell-cell interactions between neuronal and myelinating cells. Preferentially binds to alpha-2,3-linked sialic acid (By similarity).

Gene ID: 4099

UniProt: P20916

Pathways: Neurotrophin Signaling Pathway