ELP3/KAT9 antibody (C-Term)

Catalog No. ABIN7602789

This Mouse Monoclonal antibody specifically detects ELP3/KAT9 in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ELP3/KAT9 antibody (C-Term) (ABIN7602789)

Target: ELP3/KAT9 (ELP3) (Elongator complex protein 3 (ELP3))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This ELP3/KAT9 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 8B4

Product Details anti-ELP3/KAT9 Antibody

Binding Specificity: C-Term

Purpose: Anti-KAT9/ELP3 Antibody (monoclonal, 8B4)

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: identical to the related mouse sequence.

Characteristics: Anti-KAT9/ELP3 Antibody.(monoclonal, 8B4)-1. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human KAT9/ELP3, identical to the related mouse sequence.

Isotype: IgG2a

Application Details

Application Notes: Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ELP3/KAT9

Target: ELP3/KAT9 (ELP3) (Elongator complex protein 3 (ELP3))

Alternative Name: ELP3

Background:

Background: Elongator complex protein 3, also named KAT9, is aproteinthat in humans is encoded by theELP3gene. It is mapped to 8p21.1. ELP3 is the catalytichistone acetyltransferasesubunit of theRNA polymeraseII elongator complex, which is a component of the RNA polymerase II (Pol II)holoenzymeand is involved in transcriptional elongation. ELP3 supports the migration and branching ofprojection neuronsthroughacetylationof alpha-tubulin in the developingcerebral cortex. In mammals, ELP3 is important for paternalDNA demethylationafterfertilization.ELP3 is potentially involved in cellular redoxhomeostasisby mediating the acetylation ofglucose-6-phosphate dehydrogenase. Besides, ELP3 may play a role inchromatin remodelingand is involved in acetylation ofhistones H3and probablyH4.

Gene Full Name: elongator acetyltransferase complex subunit 3

Molecular Weight: 62 kDa

Gene ID: 55140

UniProt: Q9H9T3