WDR1 antibody (C-Term)

Catalog No. ABIN7602802

The Mouse Monoclonal anti-WDR1 antibody has been validated for WB and IHC. It is suitable to detect WDR1 in samples from Human and Mouse.

Quick Overview for WDR1 antibody (C-Term) (ABIN7602802)

Target: WDR1 (WD Repeat Domain 1 (WDR1))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This WDR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: 5C11C8

Product Details anti-WDR1 Antibody

Binding Specificity: C-Term

Purpose: Anti-WDR1 Antibody Picoband® (monoclonal, 5C11C8)

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-WDR1 Antibody Picoband® (monoclonal, 5C11C8) (ABIN7602802). Tested in IHC, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human WDR1, different from the related mouse and rat sequences by one amino acid.

Isotype: IgG2b

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
1. "Entrez Gene: WDR1 WD repeat domain 1". 2. Adler HJ, Winnicki RS, Gong TW, Lomax MI (May 1999). "A gene upregulated in the acoustically damaged chick basilar papilla encodes a novel WD40 repeat protein". Genomics 56 (1): 59-69. 3. Fujibuchi T, Abe Y, Takeuchi T, et al. (2005). "AIP1/WDR1 supports mitotic cell rounding". Biochem. Biophys. Res. Commun. 327 (1): 268-75.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for WDR1

Target: WDR1 (WD Repeat Domain 1 (WDR1))

Alternative Name: WDR1

Background:

Synonyms: Cofilin-2, Cofilin, muscle isoform, CFL2

Tissue Specificity: Isoform CFL2b is expressed predominantly in skeletal muscle and heart. Isoform CFL2a is expressed in various tissues.

Background: WD repeat-containing protein 1 is a protein that in humans is encoded by the WDR1 gene. It is mapped to 4p16.1. This gene encodes a protein containing 9 WD repeats. WD repeats are approximately 30- to 40-amino acid domains containing several conserved residues, mostly including a trp-asp at the C-terminal end. WD domains are involved in protein-protein interactions. The encoded protein may help induce the disassembly of actin filaments. Two transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 66 kDa

Gene ID: 9948

UniProt: O75083

Pathways: Sensory Perception of Sound