CINP antibody (N-Term)

Catalog No. ABIN7603167

This Rabbit Polyclonal antibody specifically detects CINP in WB and FACS. It exhibits reactivity toward Mouse.

Quick Overview for CINP antibody (N-Term) (ABIN7603167)

Target: CINP

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CINP antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-CINP Antibody

Binding Specificity: N-Term

Purpose: Anti-CINP Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-CINP Antibody Picoband® (ABIN7603167). Tested in Flow Cytometry, WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of mouse CINP, which shares 85.7% and 100% amino acid (aa) sequence identity with human and rat CINP, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Mouse
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Mouse
1. Grishina, I., Lattes, B. A novel Cdk2 interactor is phosphorylated by Cdc7 and associates with components of the replication complexes. Cell Cycle 4: 1120-1126, 2005. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 4/15/2010. 3. Lovejoy, C. A., Xu, X., Bansbach, C. E., Glick, G. G., Zhao, R., Ye, F., Sirbu, B. M., Titus, L. C., Shyr, Y., Cortez, D. Functional genomic screens identify CINP as a genome maintenance protein. Proc. Nat. Acad. Sci. 106: 19304-19309, 2009.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for CINP

Target: CINP

Alternative Name: Cinp

Background:

Synonyms: Trem-like transcript 1 protein,TLT-1,Triggering receptor expressed on myeloid cells-like protein 1,TREML1,TLT1,UNQ1825/PRO3438,

Tissue Specificity: Detected in platelets, monocytic leukemia and in T-cell leukemia. .

Background: Cartilage intermediate layer protein 1 is a protein that in humans is encoded by the CILP gene. The protein encoded by this gene is reported to be a component of the DNA replication complex as well as a genome-maintenance protein. It may interact with proteins important for replication initiation and has been shown to bind chromatin at the G1 phase of the cell cycle and dissociate from chromatin with replication initiation. It may also serve to regulate checkpoint signaling as part of the DNA damage response. Alternative splicing results in multiple transcript variants.

Molecular Weight: 26 kDa

Gene ID: 67236

UniProt: Q9D0V8