Bax Inhibitor 1 antibody (N-Term)

Catalog No. ABIN7603199

This anti-Bax Inhibitor 1 antibody is a Rabbit Polyclonal antibody detecting Bax Inhibitor 1 in WB, IHC, ICC and IF. Suitable for Human.

Quick Overview for Bax Inhibitor 1 antibody (N-Term) (ABIN7603199)

Target: Bax Inhibitor 1 (TMBIM6) (Transmembrane BAX Inhibitor Motif Containing 6 (TMBIM6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Bax Inhibitor 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-Bax Inhibitor 1 Antibody

Binding Specificity: N-Term

Purpose: Anti-BI-1/TMBIM6 Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-BI-1/TMBIM6 Antibody (ABIN7603199). Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human BI-1/TMBIM6, identical to the related mouse and rat sequences.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Immunofluorescence, 5 μg/mL, Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for Bax Inhibitor 1

Target: Bax Inhibitor 1 (TMBIM6) (Transmembrane BAX Inhibitor Motif Containing 6 (TMBIM6))

Alternative Name: TMBIM6

Background:

Synonyms: Prion-like protein doppel, PrPLP, Prion protein 2, PRND, DPL, UNQ1830/PRO3443

Tissue Specificity: Expressed in testis, in Sertoli cells, ejaculated spermatozoa and in seminal fluid (at protein level).

Background: Bax inhibitor 1 is a protein that in humans is encoded by the TMBIM6 gene. Enables endoribonuclease inhibitor activity and ubiquitin protein ligase binding activity. Involved in several processes, including negative regulation of RNA metabolic process, negative regulation of intrinsic apoptotic signaling pathway, and response to L-glutamate. Acts upstream of or within negative regulation of calcium ion transport into cytosol. Located in endoplasmic reticulum membrane and mitochondrial membrane. Biomarker of cervical squamous cell carcinoma and prostate carcinoma.

Molecular Weight: 35 kDa

Gene ID: 7009

UniProt: P55061

Pathways: Response to Water Deprivation, ER-Nucleus Signaling