Bax Inhibitor 1 antibody
Quick Overview for Bax Inhibitor 1 antibody (ABIN336116)
Target
See all Bax Inhibitor 1 (TMBIM6) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Specificity
- The antibody detects BI-1
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Purification
- Affinity chromatography
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Immunogen
- Synthetic peptide corresponding to residues around amino acids 210 of human Bl-1.
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Application Notes
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Western Blot: 0.5-4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 0.2 mg/mL
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Buffer
- PBS pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- -20 °C
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Storage Comment
- Store the antibody undiluted (in aliquots) at -20 °C to -70 °C.
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- Bax Inhibitor 1 (TMBIM6) (Transmembrane BAX Inhibitor Motif Containing 6 (TMBIM6))
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Alternative Name
- Bax Inhibitor 1
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Background
- Bl-1 (Bax inhibitor-1), also designated TEGT for testis enhanced gene transcript, was identified as an additional inhibitor of apoptosis. Bl-1 interacts with Bcl-2 and Bcl-xL, but not with Bax or Bak, to inhibit Bax induced apoptosis.Synonyms: BI-1, BI1, TEGT, TMBIM6, Testis-enhanced gene transcript protein, Transmembrane BAX inhibitor motif-containing protein 6
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Gene ID
- 7009
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NCBI Accession
- NP_001092046
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UniProt
- P55061
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Pathways
- Response to Water Deprivation, ER-Nucleus Signaling
Target
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