CREB3L2 antibody (N-Term)

Catalog No. ABIN7603207

The Rabbit Polyclonal anti-CREB3L2 antibody has been validated for WB, IHC, IF, ICC and FACS. It is suitable to detect CREB3L2 in samples from Human.

Quick Overview for CREB3L2 antibody (N-Term) (ABIN7603207)

Target: CREB3L2 (CAMP Responsive Element Binding Protein 3-Like 2 (CREB3L2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CREB3L2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Product Details anti-CREB3L2 Antibody

Binding Specificity: N-Term

Purpose: Anti-CREB3L2 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-CREB3L2 Antibody Picoband® (ABIN7603207). Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human CREB3L2, which shares 95.7% and 100% amino acid (aa) sequence identity with mouse and rat CREB3L2, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry, 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
1. Bejarano, P. A., Padhya, T. A., Smith, R., Blough, R., Devitt, J. J., Gluckman, J. L. Hyalinizing spindle cell tumor with giant rosettes--a soft tissue tumor with mesenchymal and neuroendocrine features: an immunohistochemical, ultrastructural, and cytogenetic analysis. Arch. Path. Lab. Med. 124: 1179-1184, 2000. 2. Panagopoulos, I., Storlazzi, C. T., Fletcher, C. D. M., Fletcher, J. A., Nascimento, A., Domanski, H. A., Wejde, J., Brosjo, O., Rydholm, A., Isaksson, M., Mandahl, N., Mertens, F. The chimeric FUS/CREB3L2 gene is specific for low-grade fibromyxoid sarcoma. Genes Chromosomes Cancer 40: 218-228, 2004. 3. Reid, R., de Silva, M. V. C., Paterson, L., Ryan, E., Fisher, C. Low-grade fibromyxoid sarcoma and hyalinizing spindle cell tumor with giant rosettes share a common t(7,16)(q34,p11) translocation. Am. J. Surg. Path. 27: 1229-1236, 2003.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for CREB3L2

Target: CREB3L2 (CAMP Responsive Element Binding Protein 3-Like 2 (CREB3L2))

Alternative Name: CREB3L2

Background:

Synonyms: CREB3L2, BBF2H7, Cyclic AMP-responsive element-binding protein 3-like protein 2, cAMP-responsive element-binding protein 3-like protein 2, BBF2 human homolog on chromosome 7 [Cleaved into: Processed cyclic AMP-responsive element-binding protein 3-like protein 2]

Background: This gene encodes a member of the oasis bZIP transcription factor family. Members of this family can dimerize but form homodimers only. The encoded protein is a transcriptional activator. Translocations between this gene on chromosome 7 and the gene fused in sarcoma on chromosome 16 can be found in some tumors. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 60 kDa

Gene ID: 64764

Pathways: Thyroid Hormone Synthesis