MME antibody (N-Term)

Catalog No. ABIN7603252

The Rabbit Monoclonal anti-MME antibody has been validated for WB, IHC and IP. It is suitable to detect MME in samples from Human and Rat.

Quick Overview for MME antibody (N-Term) (ABIN7603252)

Target: MME (Membrane Metallo-Endopeptidase (MME))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This MME antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Clone: AFGB-13

Product Details anti-MME Antibody

Binding Specificity: N-Term

Purpose: Anti-CD10 MME Monoclonal Antibody

Characteristics: Anti-CD10 MME Monoclonal Antibody (ABIN7603252). Tested in WB, IHC, IP applications. This antibody reacts with Human, Rat.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human CD10 CD10 is a transmembrane type II molecule and functions as a metallo-peptidase requiring zinc. Specifically, CD10 cleaves 1-3 amino-terminal amino acids from peptides with a preference for neutral amino acids (valine, iso-leucine, phenylalanine, leucine or alanine) . Involved in the degradation of atrial natriuretic factor (ANF) .

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000
IHC 1:50-1:200
IP 1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for MME

Target: MME (Membrane Metallo-Endopeptidase (MME))

Alternative Name: MME

Background:

Synonyms: Neprilysin,3.4.24.11 ,Atriopeptidase,Common acute lymphocytic leukemia antigen,CALLA,Enkephalinase,Neutral endopeptidase 24.11,NEP,Neutral endopeptidase,Skin fibroblast elastase,SFE,CD10,MME,EPN,

Tissue Specificity: Mainly expressed in endothelial cells lining lymphatic vessels. .

Molecular Weight: 37 kDa

UniProt: P08473

Pathways: RTK Signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration