SNCA antibody (pSer129)

Catalog No. ABIN7603269

This Rabbit Monoclonal antibody specifically detects SNCA in WB, IF and ICC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for SNCA antibody (pSer129) (ABIN7603269)

Target: SNCA (Synuclein, alpha (SNCA))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This SNCA antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: CDC-19

Product Details anti-SNCA Antibody

Binding Specificity: pSer129

Purpose: Anti-Phospho-alpha Synuclein (S129) SNCA Rabbit Monoclonal Antibody

Characteristics: Anti-Phospho-alpha Synuclein SNCA Rabbit Monoclonal Antibody (ABIN7603269). Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human Phospho-alpha Synuclein (S129)

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000
ICC/IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for SNCA

Target: SNCA (Synuclein, alpha (SNCA))

Alternative Name: SNCA

Background:

Synonyms: Alpha-synuclein,Non-A beta component of AD amyloid,Non-A4 component of amyloid precursor,NACP,SNCA,NACP, PARK1,

Tissue Specificity: Expressed principally in brain but is also expressed in low concentrations in all tissues examined except in liver. Concentrated in presynaptic nerve terminals.

Molecular Weight: 100 kDa

UniProt: P37840

Pathways: Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity